Anti-IKZF3 Antibody

Zinc finger transcription factor IKZF3 (Ikaros Family Zinc Finger Protein 3), also called Aiolos, plays a central role in B cell maturation and lymphocyte lineage commitment. This unconjugated primary antibody from Antibodies.com is raised in rabbit and supplied at 1 mg/ml in 100 µl volumes, formulated in PBS with 0.1% Sodium Azide and 50% Glycerol for handling stability.

Validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples, the polyclonal reagent recognizes multiple epitopes of IKZF3, supporting studies of isoform expression and post-translational regulation. Researchers use it to investigate immune cell development, hematopoiesis, and autoimmune disease models including systemic lupus erythematosus, where altered IKZF3 function has been documented.

Compatible with standard immunostaining protocols in fixed tissue sections and cultured lymphocytes, the reagent can be paired with secondary antibodies for signal amplification in chromatin and nuclear localization studies, and it is shipped refrigerated to preserve activity across its shelf life.