Anti-Ikaros 3 Antibody

Raised in rabbit against the Ikaros 3 zinc-finger transcription factor (also called IKZF3 and Aiolos), this polyclonal antibody from Antibodies.com recognizes an epitope in an Ikaros family member associated with B-cell maturation and lymphocyte lineage commitment. The 100 µl unconjugated preparation is validated for Western blot and ELISA workflows on human and mouse samples, supporting studies of hematopoietic development and chromatin remodeling by Ikaros-family factors.

Each lot is supplied as a liquid aliquot of polyclonal rabbit IgG, used routinely in immunoblotting of whole-cell lysates and antigen-capture ELISA against recombinant or native Ikaros 3 protein. Researchers apply this reagent to profile Ikaros family expression across B- and T-cell developmental stages, examine the interplay between Ikaros 3 and Ikaros 1 (IKZF1) in lymphocyte signaling, and investigate aberrant IKZF3 activity reported in autoimmune disease and lymphoid malignancies.