Anti-IGHMBP2 Antibody

This rabbit polyclonal antibody targets IGHMBP2 (Immunoglobulin Mu-Binding Protein 2), an ATP-dependent helicase associated with SMARD1 (spinal muscular atrophy with respiratory distress type 1) and Charcot-Marie-Tooth type 2S. Produced by Antibodies.com, the unconjugated IgG reagent ships in a 100 µL vial and has been validated for Western blot detection across human, mouse, and rat samples. The polyclonal format provides broader epitope coverage than monoclonal alternatives, supporting reliable recognition of endogenous IGHMBP2 in cell lysates and tissue homogenates. Researchers investigating neuromuscular disease mechanisms, pre-mRNA processing, or motor neuron survival can use this reagent to probe IGHMBP2 expression and corroborate genetic findings in patient-derived fibroblasts or transgenic animal models. The unconjugated design permits flexible pairing with HRP- or fluorophore-labeled secondary antibodies for chemiluminescent or fluorescent Western blot readouts.