Anti-IGFBP3 Antibody

This polyclonal reagent targets Insulin-like Growth Factor Binding Protein 3 (IGFBP3), a circulating glycoprotein that binds IGF-1 and IGF-2 to regulate growth factor bioavailability, half-life, and signaling across tissues. Beyond modulating IGF activity, IGFBP3 has intrinsic pro-apoptotic and cell-cycle arrest functions, which is why it appears frequently in oncology, metabolic disease, endocrinology, and developmental biology research.

Raised in rabbit, the antibody is validated for Western blot and ELISA workflows and cross-reacts with Human, Mouse, and Rat samples, supporting translational work from rodent models to clinical specimens. The unconjugated format leaves the choice of detection chemistry, secondary antibody, or label to the end user.

Provided as a 100 µl liquid aliquot from Antibodies.com, this Primary Antibody fits laboratories studying IGF axis regulation, tumor suppressor mechanisms, and serum biomarker development. For best results, store refrigerated and protect from repeated freeze-thaw cycles to preserve binding activity over the working shelf life of the reagent.