Anti-IGF1R (Ab-1346) Antibody

Offered through Antibodies.com, this affinity-purified reagent is a rabbit polyclonal IgG raised against a synthesized non-phosphopeptide derived from human IGF1R surrounding the tyrosine 1346 phosphorylation site (Q-P-Y(p)-A-H). Supplied at 1.0 mg/mL in a 50 µl volume, the unconjugated antibody is formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol, and it specifically detects endogenous levels of total IGF1R protein without cross-reactivity to the phosphorylated residue. The reagent is validated for Western blotting and immunohistochemistry on human samples and was affinity-purified from rabbit antiserum by epitope-specific affinity chromatography. It is shipped on wet ice at 4 °C, after which it should be aliquoted and stored at -20 °C, with freeze/thaw cycles to be avoided. Priced at 1365 SAR and intended for research use only, the polyclonal antibody is well suited to signal-transduction and receptor-tyrosine-kinase studies where total IGF1R expression must be assessed independently of site-specific phospho-status.