Anti-IGF1 Antibody

This rabbit polyclonal antibody targets IGF1 (Insulin-like Growth Factor 1), a roughly 7.6 kDa polypeptide hormone central to growth signaling, anabolic metabolism, and tissue development. Supplied as an unconjugated reagent in a 100 µl volume, it is validated by Antibodies.com for Western blot and immunohistochemistry workflows on human samples. IGF1 is synthesized mainly in the liver under growth hormone control and signals through the IGF1 receptor (IGF1R), engaging PI3K/Akt and MAPK cascades that drive cell proliferation, survival, and differentiation across many cell types. Researchers investigating growth disorders, oncology, metabolic regulation, and aging-related pathways rely on this reagent to detect endogenous IGF1 protein in cell lysates and formalin-fixed tissue sections. The polyclonal format provides broader epitope coverage than monoclonal clones, supporting reliable recognition of denatured targets on blots and consistent signal in stained sections.