Anti-IGF-1R Antibody

Raised in rabbit against insulin-like growth factor 1 receptor (IGF-1R), this unconjugated polyclonal antibody from Antibodies.com targets a transmembrane tyrosine kinase that drives growth and survival signaling across multiple tissue types.

The reagent is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, and is validated for western blot detection in human, mouse, and rat samples.

Each 50 µl vial offers enough volume for multiple immunoblotting experiments, with the polyclonal format providing broader epitope coverage suitable for recognizing both pro-IGF-1R precursor and the mature alpha and beta subunits.

Store frozen at -20°C in small aliquots to limit freeze-thaw cycles and preserve antibody activity over extended use. Investigators apply this reagent in cancer and metabolic disease research to assess receptor expression levels, ligand-induced autophosphorylation, and downstream engagement of PI3K-Akt and Ras-MAPK cascades in cell and tissue lysates.