Anti-IGF-1R (Ab-1280) Antibody

Manufactured by Antibodies.com, this research-grade reagent is a rabbit polyclonal antibody raised against the Insulin-like Growth Factor 1 Receptor (IGF-1R), raised using a synthetic peptide spanning amino acids 1278 to 1282 (S-F-Y-Y-S) of the human receptor. The antibody is supplied at the 50 µl pack size as an unconjugated, liquid formulation at 1.0 mg/mL, buffered in phosphate-buffered saline (pH 7.4) with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, and is intended for the detection of endogenous levels of total IGF-1R protein. It is validated for Western blot and immunohistochemistry workflows, with reactivity confirmed against human and mouse samples, and is purified by affinity chromatography against the immunizing peptide to minimise off-target binding. As a polyclonal reagent produced in rabbit, it offers broad epitope coverage and is dispatched from St. Louis, MO on blue ice; upon receipt it should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve antibody integrity. The product is for research use only and is not intended for diagnostic or therapeutic applications, making it suitable for signal-transduction, oncology, and metabolic-disease studies where IGF-1R signalling is being investigated at the protein level.