Anti-IFIT2 Antibody

IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2) is a cytoplasmic effector upregulated in response to type I interferons and is implicated in innate antiviral defense, translational regulation, and the cellular response to viral infection. This unconjugated Rabbit polyclonal IgG reagent from Antibodies.com is raised against the human IFIT2 sequence and is validated for Western Blot detection of endogenous IFIT2 in human cell lysates.

Provided as a 100 µl aliquot, the antibody is intended for monitoring interferon-stimulated gene (ISG) expression in cultured human cells, primary fibroblasts, or virus-infected lines, supporting studies of host-pathogen interactions, IFN signaling pathways, and the induction kinetics of innate immune effectors. The polyclonal format broadens epitope coverage and improves tolerance to minor sequence variation across IFIT2 isoforms and post-translational modifications.

Suggested uses include confirmation of IFN-α/β-driven transcriptional responses, characterization of ISG induction in viral infection models, and correlation of IFIT2 protein levels with cytokine treatment time courses. Researchers should empirically determine optimal dilution, blocking conditions, and exposure settings for their specific lysate preparation and chemiluminescent or fluorescent detection system.