Anti-IFIH1 Antibody

From Antibodies.com, this rabbit polyclonal Anti-IFIH1 Antibody targets IFIH1, the cytosolic double-stranded RNA sensor also known as MDA5, which plays a central role in antiviral innate immunity and type I interferon signaling. The unconjugated polyclonal reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples, supporting research into pattern recognition receptor function, interferon pathway activation, and the autoimmune contexts where IFIH1 variants have been implicated, including Aicardi-Goutières syndrome and systemic lupus erythematosus. Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody supports immunofluorescence imaging of IFIH1 subcellular localization, IHC tissue staining, and western blot detection of endogenous IFIH1 expression in relevant cell lines and primary cells.