Anti-IDH3B Antibody

Isocitrate dehydrogenase 3 (NAD+) beta, commonly called IDH3B, is the catalytic subunit of the mitochondrial heterotetrameric enzyme complex that converts isocitrate to alpha-ketoglutarate during the citric acid cycle. This unconjugated polyclonal antibody from Antibodies.com is raised in rabbit and selectively recognizes the IDH3B target, supporting studies of mitochondrial metabolism, TCA cycle flux, and metabolic reprogramming in cancer and neurodegeneration research.

The reagent is supplied as a 100 µl aliquot and is validated for Western blot and immunohistochemistry on human and mouse samples. Aliquot upon receipt and store at -20°C to preserve polyclonal reactivity; avoid repeated freeze-thaw cycles by preparing working stocks. The unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary reagents depending on the application, and the polyclonal nature broadens epitope coverage across the mitochondrial enzyme.

Investigators probing the role of isocitrate dehydrogenase subunits in tumor biology, neurodegenerative disease models, or basic mitochondrial biochemistry can use this reagent to confirm expression in cell lysates and fixed tissue sections.