Anti-IDH2 Antibody

Produced in rabbit and affinity-purified as a polyclonal reagent, this unconjugated antibody recognizes isocitrate dehydrogenase 2 (IDH2), a mitochondrial NADP-dependent enzyme that catalyzes the oxidative decarboxylation of isocitrate to alpha-ketoglutarate within the TCA cycle. Supplied in a 100 µl volume, the reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows and cross-reacts with human, mouse, and rat samples. Investigators studying AML, gliomas, and other malignancies with IDH2 mutations apply this reagent to assess protein expression and mitochondrial localization. The polyclonal format provides recognition of multiple epitopes on the target. For storage, aliquot and store at -20°C, avoiding repeated freeze-thaw cycles. This Antibodies.com product is provided as a primary antibody for protein detection.