Anti-ICAM3 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets human ICAM3, also known as CD50, a member of the immunoglobulin superfamily that functions as a ligand for LFA-1 (CD11a/CD18) and mediates initial contact between T lymphocytes and antigen-presenting cells during immune synapse formation. Validated for Western blot (WB) and immunohistochemistry (IHC) workflows, the reagent is supplied as a 100 µl vial of polyclonal antiserum raised in a rabbit host and reactive against human ICAM3 epitopes expressed on resting and activated leukocytes. Researchers studying T cell activation pathways, leukocyte adhesion signaling, and innate immune cell trafficking can apply this reagent to characterize ICAM3 expression on lymphocytes, monocytes, and granulocytes in cell lysates and fixed tissue sections. The unconjugated format permits flexible pairing with custom secondary labels, biotin conjugates, or fluorophores chosen downstream of the primary incubation step, and the polyclonal antibody pool supports recognition of multiple epitopes across western blot membranes and IHC preparations.