Anti-ICAM1 (phospho Y512) Antibody

Phosphorylation of intercellular adhesion molecule 1 at tyrosine 512 is a post-translational modification linked to leukocyte transmigration and inflammatory signaling cascades. This rabbit polyclonal antibody from Antibodies.com selectively recognizes the phosphorylated Y512 epitope on ICAM1, enabling researchers to probe activation-dependent changes in adhesion molecule regulation by Western blot.

Raised in rabbit and purified as a polyclonal IgG preparation, the reagent is supplied unconjugated in a 200 µl volume, providing enough material for multiple immunoblot experiments. Its reactivity is restricted to human ICAM1, making it suited for studies in human cell lines, primary cultures, and tissue lysates where phosphorylation-dependent regulation of adhesion is being investigated.

Optimized for Western blot workflows, the antibody can be paired with standard anti-rabbit HRP or fluorescent secondary reagents for chemiluminescent or imaging-based detection. Researchers studying endothelial activation, immune cell recruitment, or cytokine-driven adhesion signaling will find this phospho-specific reagent a targeted tool for dissecting the Y512 phosphorylation event on ICAM1.