Anti-ICAM1 Antibody

ICAM1 (Intercellular Adhesion Molecule 1, also called CD54) is an immunoglobulin-superfamily cell-surface glycoprotein that mediates leukocyte adhesion and transendothelial migration during inflammatory responses. It is expressed on endothelial cells, epithelial cells, and activated lymphocytes, and its expression is upregulated by pro-inflammatory cytokines such as TNF-α and IL-1β.

This unconjugated polyclonal antibody from Antibodies.com recognizes human ICAM1 and is supplied in a 100 µl vial for Western blot and immunohistochemistry workflows. The rabbit polyclonal format binds multiple epitopes on the target, supporting robust detection of endogenous protein in cell or tissue lysates and clear localization in fixed tissue sections.

Investigators working on vascular biology, immune-cell trafficking, endothelial activation, and inflammatory disease models commonly apply this reagent to track ICAM1 expression and to follow abundance changes under cytokine stimulation. The unconjugated format gives flexibility over secondary antibody choice and downstream detection chemistry, including chromogenic immunohistochemistry and standard immunoblotting with HRP- or fluorophore-conjugated secondaries.