Anti-IARS2 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this unconjugated primary antibody targets IARS2, the gene encoding mitochondrial isoleucyl-tRNA synthetase 2. The immunogen-derived IgG preparation is supplied in a 100 µl liquid vial and is validated for western blot, immunohistochemistry on paraffin and frozen sections, and immunofluorescence workflows. Reactivity has been confirmed against human and mouse samples, supporting translational work that spans cell-line models, primary tissue, and knockout or disease-mutation studies. IARS2 variants are linked to CAGSSS syndrome, combined oxidative phosphorylation deficiency, and infantile-onset neurodegeneration, so this reagent is suited to mitochondrial translation, aminoacylation, and organelle biology research. The vial should be stored refrigerated, with aliquots frozen for longer projects, and each lot is affinity-purified from rabbit serum and quality-controlled to limit lot-to-lot variability. The unconjugated format gives researchers flexibility to pair the antibody with HRP, fluorescent, or biotin secondary detection chemistries depending on the assay design.