Anti-HYOU1 Antibody

Targeting hypoxia up-regulated protein 1 (HYOU1), an endoplasmic reticulum-resident chaperone of the HSP70 family involved in the unfolded protein response and cellular adaptation to hypoxic stress, this rabbit polyclonal reagent from Antibodies.com is supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, unconjugated for flexible assay development.

The antibody has been validated for Western blot and immunohistochemistry work on human and mouse samples, supporting research into ER stress, ischemic injury, tumor hypoxia, and chaperone biology. HYOU1 (also known as ORP150 or GRP170) is induced under low oxygen conditions and protects cells from proteotoxic stress; researchers commonly deploy this reagent to follow its induction, subcellular redistribution, and expression across tumor and vascular disease models.

Recommended storage is at -20 °C in working aliquots; the glycerol co-solvent prevents freeze-thaw damage while the sodium azide preserves the solution for repeated use during extended experimental campaigns.