Anti-HVCN1 Antibody

For Western blot (WB) analysis of human protein samples, this unconjugated rabbit IgG primary antibody enables investigation of HVCN1, the voltage-gated proton channel HV1. The Antibodies.com polyclonal reagent is supplied in a 100 µL vial, allowing laboratories to pair it with a secondary antibody and detection chemistry appropriate to their immunoblotting workflow.

HVCN1 conducts protons across cell membranes and contributes to charge compensation during the phagocyte respiratory burst. It is therefore relevant to research on intracellular pH regulation, phagosomal alkalinization, membrane potential, and reactive oxygen species production in human cell models. Researchers can use the antibody to compare HVCN1 abundance among control and treated samples or to follow changes after genetic and pharmacological perturbation.

Because the primary antibody is unconjugated, it carries no directly attached reporter. This format supports flexible selection of enzyme-, fluorescence-, or chemiluminescence-based secondary detection systems. For clear interpretation, include a verified HVCN1-expressing positive control, an appropriate negative control, and molecular-weight markers, then optimize lysate loading, transfer, blocking, washing, and secondary-antibody conditions for the samples being studied. For research use only; not for diagnostic or therapeutic applications.