Anti-Human Chorionic Gonadotropin α (HCGα) Antibody

This unconjugated mouse monoclonal IgG antibody, supplied by Antibodies.com, selectively recognizes the β subunit of human chorionic gonadotropin (hCGβ), the pregnancy-associated glycoprotein hormone whose beta chain distinguishes hCG from the structurally related pituitary gonadotropins LH, FSH, and TSH. Produced in a murine host and purified as a monoclonal reagent, it is provided at 1 mg per vial in a format optimized for ELISA workflows.

Because the β subunit confers hormonal specificity, anti-hCGβ antibodies are used widely to investigate trophoblast biology, placental development, gestational trophoblastic disease, germ cell tumors that ectopically express hCG, and Down syndrome screening research. The reagent also supports studies of choriocarcinoma cell lines and reproductive endocrinology, where selective β-subunit detection separates authentic hCG activity from cross-reactive LH signals in clinical specimens. Researchers working on pregnancy biomarkers, contraceptive development, or oncology biomarker panels frequently choose this antibody to capture or detect hCGβ in conditioned media and serum-derived samples.

Supplied unconjugated, the antibody pairs readily with HRP, biotin, or fluorophore labels chosen by the user, or it can be coated directly onto ELISA plates. The monoclonal IgG format minimizes lot-to-lot variability compared to polyclonal preparations, supporting reproducible quantitative work. To preserve binding activity, researchers are advised to aliquot upon arrival and avoid repeated freeze-thaw cycles during long-term storage.