Anti-HTT Antibody

For neuroscience laboratories mapping HTT distribution in rat tissue, this unconjugated rabbit polyclonal IgG reagent from Antibodies.com offers broader epitope coverage than monoclonal alternatives, helping probe both full-length huntingtin and the smaller cleavage fragments that accumulate in disease models. The huntingtin protein, encoded by the HTT gene, contains an expanded polyglutamine tract that drives aggregate formation in neurons and glial cells during Huntington's disease, making it a key immunohistochemistry target in fixed sections. Validated specifically for IHC on rat samples, the antibody is supplied as a 100 µl liquid aliquot and can be paired with HRP- or fluorophore-conjugated secondary reagents to support either chromogenic or fluorescence detection workflows. For best stability, store at -20 °C in working aliquots and avoid repeated freeze-thaw cycles. Reactivity is restricted to rat, the host species is rabbit, and the product is intended for research use only.