Anti-HTRA1 Antibody

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com was raised against HTRA1 (High Temperature Requirement A1), a trimeric serine protease involved in protein quality control, mitochondrial homeostasis, and regulation of TGF-β family signaling. The antibody has been validated for Western blot, immunohistochemistry, and immunofluorescence applications and cross-reacts with both human and mouse HTRA1, supporting comparative studies in cell and tissue models. It is widely used to investigate loss-of-function mutations linked to CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) and to probe HTRA1 expression in age-related macular degeneration research. The reagent is supplied in a 200 µl vial as an unconjugated IgG preparation suitable for immunoblotting of placental and brain lysates, IHC on paraffin or frozen tissue sections, and IF imaging of cultured cells. For research use only.