Anti-HTR1A Antibody

The HTR1A gene encodes the 5-HT1A serotonin receptor, a Gi/Go-coupled GPCR expressed throughout the limbic system, hippocampus, dorsal raphe, and cortical regions where it modulates serotonergic tone and downstream cAMP signaling. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against HTR1A and supplied in a 50 µl vial format suitable for Western blot workflows on human, mouse, and rat samples. Researchers studying anxiety circuitry, depression models, receptor desensitization, or 5-HT pharmacology apply this reagent to probe receptor expression in brain lysates, transfected cell lines, and primary neuronal cultures. The polyclonal mixture recognizes multiple epitopes on the receptor, improving tolerance for minor sequence variation across species and supporting consistent band detection on Western blot membranes. Keep refrigerated to preserve antibody activity; the unconjugated format provides flexibility for custom HRP, biotin, or fluorophore conjugation in the lab. Each preparation is intended for research use only and is not validated for diagnostic or therapeutic applications.