Anti-HSPB8 Antibody

HSPB8 (Heat Shock Protein Family B Member 8), also referred to as Hsp22, is a small heat shock protein implicated in chaperone-assisted autophagy, cardioprotection, and the clearance of misfolded protein aggregates. Mutations in the gene have been linked to neuromuscular disorders, including Charcot-Marie-Tooth disease type 2L and distal hereditary motor neuropathy, making it a target of interest in neurodegeneration, myopathy, and protein homeostasis studies.

This polyclonal reagent from Antibodies.com is raised in rabbit and supplied at 100 µl in an unconjugated format, allowing flexible pairing with the secondary antibody of choice. Validated applications include Western blot for protein expression profiling and immunofluorescence for subcellular localization work across human, mouse, and rat samples.

Useful in investigations of stress response pathways, aggregate clearance, motor neuron health, and cardiac protection, the antibody supports cell biology, neuroscience, and cardiovascular research laboratories working on small heat shock protein function.