Anti-HSPB8 Antibody

This rabbit polyclonal antibody from Antibodies.com targets HSPB8 (Heat Shock Protein Family B Member 8), also called Hsp22, a small heat shock protein linked to chaperone-assisted selective autophagy and the cellular stress response. Supplied unconjugated in 100 µl, the reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples, making it suitable for endogenous expression profiling and subcellular localization studies.

HSPB8 is widely studied in the context of proteostasis, protein aggregate clearance, and cardioprotection under ischemic challenge. Mutations in the gene are associated with Charcot-Marie-Tooth disease type 2L and distal hereditary motor neuropathy type IIA, so the antibody is also relevant to neuromuscular and neurodegeneration research. For long-term storage, keep the vial at -20 °C and aliquot upon receipt to limit freeze-thaw cycles, and protect from light to preserve the unconjugated preparation. Researchers can apply it across cell culture-derived samples and primary tissue sections to monitor HSPB8 redistribution following heat shock or oxidative stress.