Anti-HSPB2 Antibody

Small heat shock protein HSPB2, a chaperone enriched in cardiac and skeletal muscle where it interacts with myotonic dystrophy protein kinase (DMPK) and helps preserve cytoskeletal architecture during thermal and oxidative stress, can be detected with this polyclonal rabbit antibody supplied by Antibodies.com. Provided as 100 µl of unconjugated antiserum in a single vial, the reagent is validated for western blot and immunofluorescence on human, mouse, and rat samples.

Because the antibody is polyclonal and raised in rabbit, it recognizes multiple epitopes on HSPB2, improving tolerance to minor sequence differences across species and supporting consistent band patterns in western blot of tissue lysates. The unconjugated format allows pairing with fluorophore- or enzyme-labeled secondary reagents for immunostaining of cultured myocytes and for paraffin or cryosectioned muscle tissue. The product is intended for research use only and is appropriate for studies in chaperone biology, muscle stress response, and signal transduction through the DMPK pathway.