Anti-HSPB1 (phospho S82) Antibody

Phospho-specific reagent raised in rabbit against HSPB1 (also known as HSP27) when phosphorylated at serine 82. This site is a well-characterized substrate of the p38/MK2 stress-activated kinase cascade, and detection of pS82-HSPB1 is widely used as a readout of cellular stress signaling, cytoskeletal remodeling, and cytoprotective responses in human cells and tissue sections.

The polyclonal IgG preparation from Antibodies.com is supplied at 100 µl and is validated for Western blot and immunohistochemistry on human samples. The unconjugated format gives researchers freedom to pair the antibody with secondary detection systems of their choice for immunoblotting or chromogenic tissue staining. Typical western blot bands appear near 27 kDa, consistent with the native HSP27/HSPB1 molecular weight, and immunohistochemistry on formalin-fixed paraffin-embedded sections yields cytoplasmic staining patterns in stress-responsive cell types.

Laboratories studying chaperone biology, cancer cell signaling, neurodegeneration, or cardiac and skeletal muscle stress responses rely on this Antibodies.com reagent to track activation-state dynamics of HSPB1 across their experimental systems.