Anti-HSPA4 Antibody

HSPA4 is a constitutively expressed member of the HSP110 subfamily of HSP70-family chaperones, localizing primarily to the cytosol and redistributing to the nucleus under proteotoxic stress. This rabbit polyclonal antibody from Antibodies.com is supplied as an unconjugated 100 µl aliquot intended for western blot and immunohistochemistry workflows. The reagent is validated for detection of endogenous HSPA4 in human and mouse samples, including whole-cell lysates and formalin-fixed tissue sections. Because HSPA4 participates in protein refolding, stress granule assembly, and the broader heat shock response, it is frequently examined in studies of chaperone biology, cancer cell survival, neurodegeneration, and ischemia-reperfusion injury. As a polyclonal reagent, the antibody recognizes multiple epitopes across the HSPA4 sequence, providing tolerance for denaturation-induced epitope loss that can weaken signal from monoclonal alternatives. For long-term use, freeze working aliquots to limit freeze-thaw cycles and protect from light when stored.