Anti-HSP90AB1 (phospho S254) Antibody

Heat Shock Protein 90 family member HSP90AB1 is a constitutively expressed molecular chaperone that supports client-protein folding and stability under both basal and cellular stress conditions. This rabbit polyclonal IgG reagent from Antibodies.com was raised against HSP90AB1 phosphorylated at serine 254, a modification tied to chaperone complex regulation and client-protein activation cycles.

The unconjugated antibody is supplied as a 50 µl aliquot and is validated for Western blot detection in human, mouse, and rat samples. Researchers investigating kinase signalling, stress-response pathways, and chaperone-client interactions can use this reagent to monitor phosphorylation-dependent changes in HSP90AB1 activity across cell lysates and tissue extracts.

Key features include polyclonal clonality for broader epitope coverage, IgG isotype, and cross-species reactivity in three mammalian models. The reagent is intended for research use only and supports studies of heat-shock signalling cascades, oncoprotein stabilisation, and phospho-regulated chaperone dynamics.