Anti-HSP90β Antibody

Generated in rabbit against the constitutively expressed 90 kDa chaperone HSP90β, this unconjugated polyclonal antibody from Antibodies.com is supplied in a 100 µl volume for use across multiple immunoassay formats. HSP90β plays a central role in stabilizing client signaling proteins, including kinases and transcription factors, under both basal and stress conditions, making it a widely studied target in chaperone biology.

Validated applications include western blot detection of endogenous HSP90β, immunohistochemistry localization in tissue sections, immunoprecipitation of chaperone complexes, immunofluorescence staining of fixed cells, and ELISA-based quantification. The reagent recognizes its target in human, mouse, rat, and monkey samples, supporting cross-species experimental work in cancer cell signaling, stress response, and proteostasis research.

As a polyclonal reagent, the antibody binds multiple epitopes on HSP90β, which can improve signal robustness in applications such as immunoprecipitation and western blot where denatured or partially folded targets are analyzed. The unconjugated format allows users to couple the antibody to their preferred detection chemistry, including HRP, biotin, or fluorophore conjugations, depending on experimental design. Researchers studying chaperone biology, oncology, and protein homeostasis will find this reagent useful for monitoring HSP90β expression, mapping its subcellular distribution, or pulling down interacting partners in co-immunoprecipitation workflows. For research use only.