Anti-HSP90α Antibody

Raised in rabbit, this unconjugated polyclonal reagent binds the alpha isoform of heat shock protein 90 (HSP90α), an approximately 90 kDa ATP-dependent molecular chaperone that assists client protein folding and stabilizes numerous signaling kinases. The antibody is reactive with human, mouse, and rat samples, enabling cross-species experimental work in basic and translational research programs. Validated uses include Western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and RNA immunoprecipitation, covering both protein-level analysis and RNA-protein complex capture workflows.

The reagent is supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant. Storage at -20 °C in small aliquots is recommended to limit freeze-thaw cycles and preserve binding activity; the sodium azide in the formulation also permits short-term refrigerated handling without contamination. Investigators working on chaperone biology, cancer cell signaling, or stress-response pathways can deploy this Antibodies.com reagent to probe HSP90α client interactions, confirm knockdown or inhibitor studies, and map the subcellular distribution of the chaperone in fixed tissues and cultured cells.