Anti-HSP70L1 Antibody

HSP70L1 (also called HSPA1L and Hsp70B') is a stress-inducible member of the HSP70 chaperone family that assists in folding newly synthesized proteins and refolding damaged ones under thermal or oxidative challenge. This rabbit polyclonal reagent from Antibodies.com is raised against HSP70L1 and validated for Western blotting, immunohistochemistry, and immunofluorescence on human and mouse samples. The antibody is supplied as an unconjugated preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial for multiple immunoblots and staining runs. Studies have linked altered HSP70L1 expression to inflammatory disease, including ulcerative colitis susceptibility, making this reagent a useful probe of stress-pathway responses in tissue sections, cultured cell lines, and primary cells. Store refrigerated at 4 degrees C and protect from light; avoid repeated freeze-thaw cycles to preserve binding activity. The polyclonal format enables recognition of multiple epitopes across the HSP70L1 protein, improving signal in IHC and IF where conformational accessibility varies between samples.