Anti-HSP60 Antibody

This polyclonal antibody from Antibodies.com targets HSP60, a mitochondrial chaperonin that assists in the proper folding of nascent polypeptides and is upregulated under cellular stress conditions. The reagent is raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, shipped as a 100 µl liquid aliquot that is ready to dilute directly into standard immunodetection workflows.

Validated for Western blot, immunohistochemistry, and immunofluorescence, the antibody detects both human and mouse HSP60, supporting cross-species studies of mitochondrial stress, chaperone biology, and chaperoninopathies. Researchers commonly apply it to characterize mitochondrial damage in neurodegeneration models, examine heat shock responses in cancer cell lines, and probe bacterial and mitochondrial HSP60 homologues in infectious disease and autoimmune contexts such as rheumatoid arthritis and chronic inflammatory conditions.

As an unconjugated primary reagent, it pairs cleanly with HRP- or fluorophore-labeled secondary antibodies, enabling flexible detection across chromogenic and fluorescence platforms. The product is stored at -20 °C in working aliquots to preserve activity across multiple freeze-thaw cycles, and the polyclonal format improves the likelihood of recognizing multiple epitopes on the HSP60 target.