Anti-HSP10 Antibody

A polyclonal antibody raised in rabbit for detecting the mitochondrial chaperone HSP10 (also called CPN10 or HSPE1), supplied by Antibodies.com as an unconjugated primary antibody in a 100 µl vial. This reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows, and shows reactivity against human, mouse, and rat samples, making it a versatile tool for comparative studies of the heat-shock response across model organisms.

HSP10 partners with HSP60 to form the mitochondrial chaperonin complex responsible for folding imported matrix proteins, and its expression rises under cellular stress, in certain tumor types, and in models of mitochondrial dysfunction. Researchers use it to probe mitochondrial biogenesis, the unfolded protein response, and chaperone-assisted protein refolding in cell and tissue samples. The polyclonal format improves the likelihood of detecting multiple epitopes on the small ~10 kDa HSP10 subunit, and the unconjugated presentation allows flexible pairing with secondary antibodies labelled to the user's preferred reporter. Suitable for use on fixed sections (IHC), cultured cells (IF), and lysates (WB).