Anti-HSD17B8 Antibody

The HSD17B8 target encodes a 17β-hydroxysteroid dehydrogenase, also known as HKE6, that localizes to mitochondria and contributes to estrogen metabolism and mitochondrial fatty acid elongation. This Rabbit polyclonal IgG is supplied by Antibodies.com in a 200 µl volume as an unconjugated reagent validated for WB detection of the human protein.

The antibody is applied in western blot workflows using denatured human cell or tissue lysates and pairs with an appropriate secondary antibody for chemiluminescent or colorimetric readout. Researchers investigating steroid hormone interconversion, mitochondrial lipid biosynthesis, or the link between HSD17B8 variants and progressive myoclonus epilepsy (EPMR) probe endogenous protein levels encoded on chromosome 6p25.1. The polyclonal format increases the chance of recognizing multiple epitopes on HSD17B8, which can help when probing alternative isoforms from the same locus.