Anti-HRAS + KRAS + NRAS Antibody [Assigned #A11059]

RAS-family small GTPases including HRAS, KRAS, and NRAS act as molecular switches in the MAPK/ERK signaling cascade, coupling activated receptors to downstream effectors that control proliferation, differentiation, and survival. A pan-RAS reagent that recognizes all three isoforms is useful in pathway studies and supports screening of tumor samples in cancer research workflows.

This unconjugated rabbit monoclonal IgG from Antibodies.com targets a conserved region shared across HRAS, KRAS, and NRAS, enabling detection of endogenous and overexpressed targets in cell lysates and tissue sections. Validations cover Western blot, immunofluorescence, and immunoprecipitation applications, with reactivity confirmed in human, mouse, and rat samples. The unconjugated format allows flexible pairing with HRP-, fluorophore-, or biotin-labeled secondary reagents of the user's choice.

Supplied as 200 µl of liquid, the reagent should be stored refrigerated between uses and handled with standard aseptic technique to preserve activity across multiple experiments.