Anti-HOMER1 Antibody

HOMER1 organizes group 1 metabotropic glutamate receptors, NMDA receptor complexes, and inositol trisphosphate receptors at excitatory synapses, and this polyclonal antibody raised in rabbit against the HOMER1 scaffold is supplied by Antibodies.com as an unconjugated reagent for tracking that postsynaptic machinery in neuroscience research. Reliable HOMER1 detection supports studies of synaptic plasticity, neuronal development, and calcium-dependent signaling cascades, where changes in scaffold expression are tied to Fragile X, autism, addiction, and ischemic stroke models.

Validated for Western blot and immunohistochemistry on human and mouse samples, the antibody covers the two most common readouts used to map HOMER1 distribution across brain regions, primary neuronal cultures, and transfected cell lines. Supplied as a 100 µl liquid aliquot of rabbit serum-derived IgG with no fluorophore or enzyme attached, it pairs freely with HRP, biotin, or fluorescent secondary reagents chosen to match each experimental design. Refrigerated short-term handling preserves activity, and aliquoting before freezing at low temperature extends usability across many blots and staining runs. Researchers can probe HOMER1 alongside PSD-95 and mGluR markers for comparative expression analysis.