Anti-HNRNPU Antibody [Assigned #A9907]

Mouse monoclonal IgG reagent raised against heterogeneous nuclear ribonucleoprotein U (HNRNPU), the approximately 120 kDa nuclear DNA- and RNA-binding factor also known as scaffold attachment factor A (SAF-A). Supplied by Antibodies.com as an unconjugated 100 µl liquid aliquot, this clone carries the assigned designation #A9907 and is validated for Western blot detection of the human target. The unconjugated format lets researchers pair the primary with HRP- or fluorophore-conjugated secondaries of their choice, supporting chemiluminescent, chromogenic, or fluorescence readout on PVDF or nitrocellulose membranes.

HNRNPU concentrates in the nucleus, where its RGG RNA-binding motif and scaffold/matrix attachment region (S/MAR) DNA-binding activity contribute to chromatin organization, pre-mRNA processing, mRNA stability, and telomere maintenance. Investigators studying HNRNPU loss-of-function variants linked to X-linked intellectual disability (XLID), or profiling autoantibody reactivity against nuclear antigens in connective-tissue disease serology, rely on HNRNPU-specific monoclonal clones such as this to distinguish isoform expression across patient-derived samples and cell models.

For research use only. To preserve IgG activity, store refrigerated and protect from repeated freeze-thaw cycles by aliquoting on first use.