Anti-HNRNPL Antibody

HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L) is an abundant RNA-binding protein that regulates pre-mRNA splicing, mRNA stability, and translation. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against human HNRNPL and validated for Western blot (WB) and immunohistochemistry (IHC) workflows.

Provided as a 100 µl liquid aliquot, the reagent is a versatile tool for studies of post-transcriptional gene regulation, alternative splicing events, and RNA processing in mammalian cells and tissue sections. Because the immunogen targets an epitope conserved across human HNRNPL isoforms, the antibody supports detection of the full-length protein as well as several alternatively spliced variants commonly observed in cancer cell lines and primary tissues.

Typical experimental uses include probing cytoplasmic and nuclear fractions by WB to monitor HNRNPL expression under stress, hormone, or differentiation stimuli, and chromogenic or fluorescent IHC on formalin-fixed paraffin-embedded (FFPE) sections to map HNRNPL distribution in tumor and normal tissue microarrays. The unconjugated format allows pairing with HRP-, biotin-, or fluorophore-conjugated secondary reagents to fit standard laboratory detection chemistries.

Store refrigerated and protect from light; for long-term storage, aliquot and keep frozen to minimise freeze-thaw cycles. The product is supplied as a vial intended for research use only applications in molecular biology, cell biology, and histology laboratories.