Anti-HNRNPD Antibody

HNRNPD, also known as AUF1 (AU-rich element RNA-binding protein 1), is a key post-transcriptional regulator that controls the stability and rapid turnover of mRNAs bearing AU-rich elements in their 3' untranslated regions. This rabbit polyclonal antibody from Antibodies.com is raised against HNRNPD and supplied as 100 µl of unconjugated antiserum in a single-use vial format, ready for Western blot and immunohistochemistry workflows.

The reagent detects endogenous HNRNPD in human, mouse, and rat samples, supporting translational research into mRNA decay, cytokine regulation, inflammatory signaling, cell-cycle control, and tumor biology, where altered AUF1 expression has been linked to cancer, cellular senescence, and oxidative stress responses. Recommended storage at -20 °C in working aliquots preserves antibody activity across multiple freeze-thaw cycles, and the polyclonal format provides broader epitope recognition across the four known HNRNPD isoforms (p37, p40, p42, p45) than most monoclonal alternatives, making it a practical choice for surveillance of isoform-specific shifts in expression.