Anti-hnRNP Q Antibody

Anti-hnRNP Q Polyclonal Antibody for Multiple Research Applications

This rabbit polyclonal antibody from Antibodies.com targets heterogeneous nuclear ribonucleoprotein Q (hnRNP Q), also known as SYNCRIP, an RNA-binding protein involved in pre-mRNA splicing, mRNA transport, translation regulation, and RNA stability. The unconjugated reagent is supplied at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol as an anti-microbial and cryoprotective additive, packaged as a 100 µL vial suitable for routine laboratory use.

Validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), the antibody shows reactivity with human, mouse, and rat samples, supporting comparative studies in translational neuroscience, stem cell biology, and oncology where hnRNP Q expression patterns are investigated across species and tissue types.

hnRNP Q (SYNCRIP) localizes to cytoplasmic RNA granules, contributes to dendritic mRNA transport in neurons, and participates in viral RNA replication cycles, including those of hepatitis B and poliovirus, making it a relevant target for studies of post-transcriptional gene regulation and host-pathogen interactions. The polyclonal format allows recognition of multiple epitopes on the target, which can be advantageous when detecting isoforms or post-translationally modified forms of the protein.

For storage, the product should be kept at -20 °C, ideally in small working aliquots to limit freeze-thaw cycles; the glycerol content helps preserve antibody activity during routine handling. This reagent is supplied for research use only and is not validated for diagnostic or therapeutic applications.