Anti-hnRNP M Antibody

Supplied by Antibodies.com, this affinity-purified polyclonal antibody was raised in rabbit against heterogeneous nuclear ribonucleoprotein M (hnRNP M), a nuclear RNA-binding protein that participates in pre-mRNA processing, alternative splicing regulation, and mRNA stability control.

Provided as an unconjugated reagent in a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and shows reactivity with hnRNP M from human, mouse, and rat samples, supporting comparative studies across model organisms and cross-species expression profiling.

Polyclonal coverage enables recognition of multiple epitopes on the target, which is useful when probing for isoforms, splice variants, or post-translationally modified forms of hnRNP M. Typical laboratory uses include probing nuclear and whole-cell lysates by immunoblotting, localizing hnRNP M in fixed tissue sections by IHC staining, and immunoprecipitating the protein from cell extracts as a step toward characterizing spliceosome composition and RNA-protein interactions.

For storage, hold aliquots at -20°C and avoid repeated freeze-thaw cycles to preserve activity; the 50% glycerol formulation helps protect the antibody from freeze damage during routine handling.