Anti-hnRNP A2 / B1 Antibody

This unconjugated rabbit polyclonal antibody targets hnRNP A2 / B1, a pair of closely related heterogeneous nuclear ribonucleoproteins generated by alternative splicing of the HNRNPA2B1 gene. These proteins act as RNA-binding factors in pre-mRNA processing, mRNA transport, translation regulation, and stress granule assembly, and have been investigated as autoantigens in autoimmune disease and as biomarkers of premalignant lung lesions. Antibodies.com supplies the reagent at 100 µL per vial as a polyclonal rabbit antiserum.

The antibody is validated for human and mouse reactivity, with demonstrated use in western blot, immunohistochemistry, immunofluorescence, and ELISA assays. Researchers in RNA biology, telomere regulation, and cancer cell signalling use this reagent to probe endogenous hnRNP A2 and hnRNP B1 levels in cell culture lysates, tissue sections, and fixed specimens. Shipped as a single vial of unconjugated antiserum, the antibody can be paired with HRP, biotin, or fluorophore-conjugated secondary reagents for flexible assay design.