Anti-HNF1B Antibody

Generated in rabbit as a polyclonal IgG reagent, this unconjugated primary antibody recognizes HNF1B, a homeodomain-containing transcription factor implicated in kidney, pancreas, and genitourinary tract development. Antibodies.com supplies the antibody at 100 µl per vial as a liquid formulation validated for western blot detection across human, mouse, and rat samples.

HNF1B, also known as TCF2, participates in Wnt signaling and embryonic organogenesis and is investigated in renal cyst research, clear cell carcinoma of the ovary, and MODY5 diabetes studies. Researchers apply the reagent in western blotting workflows to probe HNF1B expression in cell lysates and tissue homogenates, where the protein is commonly observed around 60 to 65 kDa.

Aliquoting on first use preserves activity across repeated freeze-thaw cycles; storage at -20 °C is recommended for long-term stocks, with refrigeration suitable for active working aliquots. Each lot is delivered with documented reactivity profiles for the indicated species, supporting reproducible western blot results in basic and translational research settings.