Anti-HMGN2 Antibody

Raised in rabbits against the nucleosome-binding chromatin protein HMGN2, this polyclonal primary antibody recognizes an epitope on a member of the HMGN family implicated in chromatin unfolding, transcription modulation, and DNA-templated processes in vertebrate cells. The unconjugated reagent is formulated at 1 mg/ml in PBS supplemented with 0.1% sodium azide as preservative and 50% glycerol as cryoprotectant, packaged as 100 µl per vial. Validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), the reagent supports detection of HMGN2 in fixed tissue sections, whole-cell lysates, and immunostaining workflows alike. Confirmed reactivity covers human and rat samples, enabling comparative studies between patient-derived material and rodent model systems in translational research settings. The unconjugated format permits pairing with secondary reagents such as HRP, biotin, or fluorophore-conjugated antibodies, letting laboratories select their preferred detection chemistry without steric hindrance from a pre-attached label. For storage, refrigerated short-term use at 4 °C is appropriate, while longer-term preservation at -20 °C with aliquoting helps protect the polyclonal pool from degradation; repeated freeze-thaw cycles should be avoided to preserve titre. Antibodies.com supplies this reagent for chromatin biology research, gene regulation studies, and investigations of HMGN family protein function in normal development and disease contexts.