Anti-HMGB1 Antibody

The recombinant monoclonal antibody targeting High Mobility Group Box 1 (HMGB1) from Antibodies.com is supplied as a 100 µl aliquot in 1×TBS buffer (pH 7.4) supplemented with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. Produced in rabbit hosts, this unconjugated primary antibody supports multiple immunodetection workflows including Western blot, immunocytochemistry/immunofluorescence, immunohistochemistry, and flow cytometry. It has been validated for reactivity against human, mouse, and rat samples, making it a practical reagent for translational research, cell biology studies, and inflammation-related investigations. The clone is engineered recombinantly, ensuring batch-to-batch consistency and reproducibility across experiments. Researchers studying chromatin-associated proteins, nuclear damage signaling, or HMGB1 release as a damage-associated molecular pattern (DAMP) in sepsis, cancer, or autoimmune models can apply this reagent to track protein expression and localization in fixed cells, tissue sections, and lysate preparations.