Anti-HMGA2 Antibody

Produced by Antibodies.com, this rabbit polyclonal reagent targets the High Mobility Group AT-Hook 2 (HMGA2) chromatin-associated transcription factor. HMGA2 binds AT-rich regions in the minor groove of DNA to modulate chromatin architecture and is implicated in embryonic development, mesenchymal stem cell regulation, and oncogenic transformation in several tumor types, including lipomas, leiomyomas, and pancreatic adenocarcinoma.

The antibody is supplied as an unconjugated 100 µL aliquot raised in rabbit, validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human-derived samples. For short-term use, store refrigerated at 4 °C; aliquot and freeze at -20 °C for longer term storage, avoiding repeated freeze-thaw cycles. Researchers investigating gene expression regulation, chromatin remodeling, differentiation pathways, or tumor biology can deploy this reagent to detect endogenous HMGA2 protein levels in cell lysates and formalin-fixed tissue sections.