Anti-HMGA1 Antibody

A non-histone chromatin-associated architectural transcription factor, HMGA1 binds AT-rich regions in the minor groove of DNA and remodels chromatin structure to regulate gene expression. From Antibodies.com, this rabbit polyclonal reagent is raised against HMGA1 and is widely applied in oncology research, where aberrant HMGA1 overexpression correlates with neoplastic transformation, tumor progression, and metastatic behavior across multiple cancer types. The unconjugated antibody is validated for Western blot and reacts with Human and Mouse samples, supporting translational comparisons between patient-derived material and model systems. Supplied as 100 µl at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2, it is ready for direct dilution into standard immunoblotting workflows. Store refrigerated and protect from light. For research use only.