Anti-HLA-DRB3 Antibody

This polyclonal reagent from Antibodies.com targets the HLA-DRB3 beta chain subunit of MHC class II molecules, enabling researchers to investigate antigen presentation pathways and immune response genetics in human samples. The antibody is raised in rabbit and is supplied as an unconjugated preparation in a 100 µl volume, allowing flexible labeling with secondary reporters of the researcher's choice. It has been validated for western blot detection of the DRB3-encoded beta chain and for immunofluorescence imaging of MHC class II expression on cell surfaces and within intracellular compartments.

This reagent is reactive with human HLA-DRB3 and supports applications such as characterizing HLA-DR isoform expression in lymphoblastoid cell lines, examining class II variability in transplantation research, and probing DRB3 involvement in autoimmune disease models. Refrigerate upon arrival and aliquot to preserve activity across multiple freeze-thaw cycles; protect from light to maintain reagent integrity for repeated western blot and immunofluorescence experiments.