Anti-HLA-DRB3 Antibody

Produced in rabbits as an unconjugated polyclonal antiserum, this reagent targets the beta subunit of the human HLA-DRB3 protein, a class II major histocompatibility complex (MHC) molecule that functions in antigen presentation to CD4-positive T lymphocytes. Distributed by Antibodies.com, the antibody is supplied as 100 µl of ready-to-use reagent validated for western blot (WB) and immunohistochemistry (IHC) workflows on human tissue samples.

HLA-DRB3 is one of several DRB paralogs expressed selectively in individuals carrying certain DRB1 haplotypes, making this reagent useful for studies in transplantation immunology, HLA typing characterization, autoimmune disease research, and investigations of peptide binding and immune recognition.

The polyclonal host response recognizes multiple epitopes on the DRB3 chain, supporting detection in denaturing western blots as well as IHC preparations, while the unconjugated format allows researchers to pair it with their preferred secondary detection reagents and reporter systems.