Anti-HLA-A Antibody

This unconjugated rabbit polyclonal primary antibody from Antibodies.com targets HLA-A, a major histocompatibility complex class I molecule that presents endogenous peptide antigens to CD8+ cytotoxic T lymphocytes. Raised in rabbit against the human HLA-A heavy chain, the reagent is supplied as 100 µl of polyclonal antiserum suitable for western blot, immunohistochemistry, and immunofluorescence workflows.

The antibody specifically recognizes native and denatured human HLA-A, supporting studies of antigen presentation, allorecognition in transplantation biology, and MHC-I surface expression on tumor and immune cell populations. As an unconjugated reagent, it accepts secondary detection chemistries such as HRP, biotin, and fluorophore conjugates selected by the researcher for signal generation.

Investigators working on autoimmune disease, tumor immune evasion, peptide-MHC binding studies, and HLA-typed donor-recipient screening commonly deploy this reagent to profile HLA-A expression across cultured cell lines, primary tissues, and biopsy specimens. Reactivity is restricted to human samples, and the product is intended for research use only in laboratory settings.